Up to 10 billion B-Cells are produced by our bodies each day. However, the total number of lymphocytes, including B-Cells, rises when we get sick. So, read forward to know what do B-Cells do in the body.
Our immune system activates hordes of sentinel cells the instant our body is under attack and gives them orders to combat viruses, bacteria, and other pathogens that are attempting to damage us.
We must first describe the many cell types that make up our blood before moving on to the discussion of B-Cells.
Classification of blood cells
Three major categories can be used to classify human blood cells:
1. RBCs, also known as erythrocytes
These cells are in charge of carrying oxygen to the body’s tissues and carrying carbon dioxide back to the lungs for exhalation.
2. Thrombocytes vs platelets
When you are harmed, these amazing warriors assist with wound healing and stop bleeding, so you don’t lose too much blood.
3. WBCs, also known as leukocytes
They guard your immune system and support your defences against bacteria, viruses, and other foreign invaders that could harm you.
When invaders, such as viruses and deadly bacteria, enter your body, brave B-Cells race to defend you. A sore throat, stuffy nose, and these small bacteria’ poor behaviour might occasionally make you feel ill. But B-Cells work hard to stop that from happening, along with other Biowarriors and your autonomic nervous system.
What Makes B Cells?
Bone marrow, the supple, gelatinous tissue found inside our bones, is where B-cells are made.
Our bone marrow is amazing since it produces the so-called hematopoietic stem cells (HSCs).
Now, don’t be put off by these intimidating terms!
You need to know that HSCs produce erythrocytes, thrombocytes, and leukocytes, among other types of blood cells.
B-cells remain in the bone marrow after they have completed development to mature, and as they do so, they prepare to fight off pathogens.
Imagine that B-Cells mature as they get older and develop as they enter a boot camp to get ready for their first mission. B-Cells are given weaponry to employ in combat in this bone marrow Bootcamp—the so-called receptors.
More About It
The B-Cells are then put to the test by our body to see how developed and effective their receptors are.
Positive selection occurs on B-cells with effective receptors, which are prepared to bind to dangerous pathogens and inhibit their spread. They carry on their way to secondary lymphoid organs (SLOs), which include the spleen and lymph nodes, where they wait to be enlisted for combat.
However, some B-Cells are unable to survive. They begin to perceive even beneficial germs as a threat. And that can also contribute to the onset of autoimmune illnesses, in which the body erroneously attacks healthy tissues after mistaking them for threats.
Therefore, in order to avoid that, our body uses negative selection to deal with the self-reacting B-Cells. The immune system alters the receptors, so they no longer target the good guys, and our body orders the B-Cells to self-destruct (a process known as apoptosis).